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  • Title: DTNB inhibits calcium response of rat brain cortical slices to anoxia of various duration.
    Author: Semenov DG, Samoilov MO, Lazarevich EV.
    Journal: Bull Exp Biol Med; 2001 Jun; 131(6):526-8. PubMed ID: 11586396.
    Abstract:
    The effects of DTNB on changes in intracellular Ca(2+) content in slices of rat cortex induced by 2- or 10-min anoxia were studied fluorometrically. DTNB (200 microM) prevented excessive intracellular Ca(2+) accumulation during and after 10-min anoxia and moderate increase in Ca(2+) content induced by 2-min anoxia. Our results suggest that redox sites of NMDA receptors participates in both pathogenic and adaptive Ca(2+)-mediated processes activated by anoxia.
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