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  • Title: Effect of diet on the metabolism and toxicology of drugs.
    Author: Ioannides C, Parke DV.
    Journal: J Hum Nutr; 1979 Oct; 33(5):357-66. PubMed ID: 115915.
    Abstract:
    The human organism is continuously exposed to a variety of xenobiotics, as drugs, pesticides, food additives and many environmental contaminants, all of which are potentially toxic. The body metabolizes these highly reactive chemicals to pharmacologically-inert compounds, which are readily eliminated from the body. This process of deactivation is dependent on nutritional status. Malnutrition, almost invariably, leads to a reduced capacity to deactivate these exogenous materials with consequent increase in toxicity.
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