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  • Title: [Exploration of the mechanism of skin expansion].
    Author: He Z, Yuan Z, Yan G.
    Journal: Zhonghua Zheng Xing Wai Ke Za Zhi; 2000 Mar; 16(2):84-6. PubMed ID: 11593625.
    Abstract:
    OBJECTIVE: In order to explore the mechanism of skin expansion technique (SET). METHODS: Domestic dogs were used in this experiment. The epidermal mitotic activity, capillary blood flow change of the expanded flap were observed with microspectrophotometer and radioactive microsphere technique. RESULTS: 1. The epidermis of expanded skin was significantly thicker than that of other groups (P < 0.05). 2. The epidermal mitotic activity was elevated significantly(P < 0.01). 3. The capillary blood flow of expanded flaps increased significantly (P < 0.01). CONCLUSIONS: 1. The surplus skin produced by SET is the result of replication, not compensation. 2. SET increases skin blood flow, therefore enlarges the survival area of an expanded flap.
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