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  • Title: Neonatal purpura fulminans due to homozygous protein C deficiency.
    Author: Ezer U, Misirlioglu ED, Colba V, Ogoz E, Kurt C.
    Journal: Pediatr Hematol Oncol; 2001; 18(7):453-8. PubMed ID: 11594708.
    Abstract:
    Severe and recurrent purpura fulminans developed in a Turkish boy at 1 week of age. Initial coagulation studies performed were compatible with disseminated intravascular coagulation. Subsequent investigations showed that the patient had homozygous and his healthy parents had heterozygous protein C deficiency. The episodes of purpura fulminans were controlled by infusions of fresh frozen plasma and heparinization. Oral anticoagulant therapy was given in the symptom-free period.
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