These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Distinct roles for Distal-less genes Dlx3 and Dlx5 in regulating ectodermal development in Xenopus.
    Author: Luo T, Matsuo-Takasaki M, Sargent TD.
    Journal: Mol Reprod Dev; 2001 Nov; 60(3):331-7. PubMed ID: 11599044.
    Abstract:
    In vertebrates, there are six or more copies of genes related to the Drosophila pattern formation homeodomain gene Distal-less. Among this family, Dlx3 and Dlx5 share extensive sequence homology and have similar, but distinctive, expression patterns, suggesting that these two factors may have substantially redundant developmental functions. Here we show that at the earliest phases of embryogenesis in Xenopus, there are significant differences between Dlx3 and Dlx5 expression and that this correlates with different functions in the restriction of neural crest and neural plate boundaries, respectively.
    [Abstract] [Full Text] [Related] [New Search]