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  • Title: Antimicrobial susceptibilities of 1,730 Haemophilus influenzae respiratory tract isolates in Spain in 1998-1999.
    Author: Marco F, García-de-Lomas J, García-Rey C, Bouza E, Aguilar L, Fernández-Mazarrasa C, Spanish Surveillance Group for Respiratory Pathogens.
    Journal: Antimicrob Agents Chemother; 2001 Nov; 45(11):3226-8. PubMed ID: 11600386.
    Abstract:
    A beta-lactamase prevalence of 23% was found among 1,730 Haemophilus influenzae isolates. Ampicillin susceptibility was 70%, and 12% of beta-lactamase-negative strains presented diminished susceptibility to ampicillin (BLNAR phenotype). Susceptibility of 90% was found for cefaclor and clarithromycin, whereas it was nearly 100% for cefotaxime, cefixime, azithromycin, and cefuroxime. Ciprofloxacin-resistant (0.1%) and beta-lactamase-positive amoxicillin/clavulanate-resistant (BLPACR) phenotypes (0.1%) are anecdotal so far.
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