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  • Title: Cathodic adsorptive stripping square-wave voltammetry of the anti-inflammatory drug meloxicam.
    Author: Radi AE, Ghoneim M, Beltagi A.
    Journal: Chem Pharm Bull (Tokyo); 2001 Oct; 49(10):1257-60. PubMed ID: 11605650.
    Abstract:
    The adsorptive behavior of the anti-inflammatory drug meloxicam was studied by cyclic, differentia-pulse and square-wave voltammetry on a hanging mercury drop electrode (HMDE). The drug was accumulated at HMDE and a well-defined stripping peak current was obtained at -1.42 V vs. Ag/AgCl (saturated KCl) electrode in acetate buffer solution (pH 5.0). A voltammetric procedure was developed for the determination of meloxicam using square-wave cathodic adsorptive stripping voltammetry (SW-CASV). The optimum working conditions for the determination of the drug were established. The analysis of meloxicam in human plasma was carried out satisfactorily.
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