These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Bumetanide--acute and long term studies of a new high potency diuretic.
    Author: Murdoch WR, Auld WH.
    Journal: Postgrad Med J; 1975 Jan; 51(591):10-4. PubMed ID: 1161670.
    Abstract:
    The properties of a new diuretic, bumetanide, were investigated in ten normal volunteers, and sixty-eight patients with fluid retention. It had a rapid action virtually complete in 4 hr with an effect on water and electrolyte excretion similar to that of frusemide. It was highly potent, 1 mg producing an effect comparable to 48 mg frusemide in normal subjects, and about 40 mg in oedematous subjects in controlled short-term experiments. In long-term studies in forty-eight patients extending over periods up to 51 weeks it was found to be effective in controlling oedema. There was a low incidence of electrolyte complications and no other biochemical abnormalities or haematological complications were attributed to the drug. Bumetanide was well tolerated by patients. A drug rash was observed in two cases.
    [Abstract] [Full Text] [Related] [New Search]