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  • Title: Distribution of concanavalin A receptor sites on specific populations of embryonic cells.
    Author: Roberson M, Neri A, Oppenheimer SB.
    Journal: Science; 1975 Aug 22; 189(4203):639-40. PubMed ID: 1162345.
    Abstract:
    The early 32- to 64-cell stage of the sea urchin embryo consists of three cell types, easily distinguishable by size: micromeres, mesomeres, and macromeres. Only the micromeres are migratory. Treatment of dissociated sea urchin embryo cells with fluorescein-labeled concanavalin A (Con A) revealed a Con A-induced highly clustered or capped distribution of receptor sites on the micromeres. Concanavalin A did not induce significant clustering or capping of receptor sites on the mesomeres or macromeres. The results indicate that Con A receptor sites are more mobile on specific population of malignant-like migratory embryonic cells.
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