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Title: Cardiovascular effects of pancuronium bromide in mongrel dogs. Author: Reitan JA, Warpinski MA. Journal: Am J Vet Res; 1975 Sep; 36(9):1309-11. PubMed ID: 1163867. Abstract: The cardiovascular effects of a new nondepolarizing muscle relaxant, pancuronium bromide, were studied in mongrel dogs. Small, but significant, increases in mean arterial blood pressure were observed after each of 2 intravenous doses (0.01 mg/kg and 0.1 mg/kg) were given. Heart rate increased significantly in dogs administered the larger dosage, and indexes of ventricular functions demonstrated a trend toward positive cardiac inotrophy after either the large or the small dose.[Abstract] [Full Text] [Related] [New Search]