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  • Title: Ovarian giant cell tumor with cystadenocarcinoma.
    Author: Veliath AJ, Sankaran V, Aurora AL.
    Journal: Arch Pathol; 1975 Sep; 99(9):488-91. PubMed ID: 1164251.
    Abstract:
    A 25-year-old woman had a malignant ovarian tumor with two distinct tumor patterns: pseudomucinous cystadenocarcinoma and malignant giant cell tumor of bone. One area of the tumor had a lining of tall columnar epithelium with abundant mucin production; however, another area of the same tumor had a number of large multinucleated giant cells that resembled osteoclasts, intermingled with mononuclear stromal cells. There was no blending of the two tumor patterns. Mitoses were frequent in both areas. A probable histogenesis of the tumor from a malignant teratoma is suggested.
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