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  • Title: [Surface structure of the macrophages and lymphocytes in their interaction under conditions of antigenic stimulation observed with the scanning electron microscope].
    Author: Favorskaia IuN, Krymskiĭ LD, Nestaĭko GV.
    Journal: Arkh Patol; 1975; 37(8):33-9. PubMed ID: 1167113.
    Abstract:
    The surface structure of macrophages, lymphocytes of peritoneal exudate and lymphocytes from the lymphatic node of intact, stimulated with meat-pentone broth and induced with antigen mice was studied using raster electron microscopy. Lymphocytes outwardly did not differ from each other irrespective the source of their origin. Macrophages obtained from the peritoneal cavity of the stimulated mice morphologically differed from those isolated from intact mice. Antigenic stimulation of macrophages made it possible to investigate the dynamics of absorption and digestion of sheep corpuscles, as well as the morphology of this process. It was established that in combined cultivation of macrophages and lymphocytes under conditions of antigenic stimulation the number of contacts between lymphocytes and between lymphocytes and macrophages considerably increased. The cytoplasmic ponticulus connecting cells was formed mostly at the expense of a single finger-shaped growth of the lymphocyte membrane.
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