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  • Title: Comparative in vitro activities of five quinolone antibiotics, including gemifloxacin, against clinical isolates.
    Author: Gönüllü N, Aktaş Z, Salcioglu M, Bal C, Ang O.
    Journal: Clin Microbiol Infect; 2001 Sep; 7(9):499-503. PubMed ID: 11678934.
    Abstract:
    The in vitro activities of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin and gemifloxacin against 343 clinical isolates were compared. Gemifloxacin showed the greatest activity, with MIC90 values as low as 0.03-0.25 mg/L against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, methicillin-susceptible Staphylococcus aureus and Klebsiella pneumoniae, while methicillin-resistant Staphylococcus aureus, Enterococcus spp., Pseudomonas spp., Acinetobacter spp., Escherichia coli and Enterobacter spp. strains exhibited low rates of susceptibility to all five fluoroquinolones.
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