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  • Title: [Rhinocerebral mucormycosis: apropos of 4 new Tunisian cases].
    Author: Makni F, Cheikh-Rouhou F, Ayadi A, Abdelmoula M, Karray F, Maaloul I, Khemakhem B.
    Journal: Bull Soc Pathol Exot; 2001 Aug; 94(3):239-42. PubMed ID: 11681218.
    Abstract:
    Mucormycosis is a rare opportunistic infection but a fulminant disease. We report the 4 first cases of rhinocerebral mucormycosis diagnosed in Sfax region (Tunisia). They occurred in insulin dependent diabetes and developed varying clinical manifestations from facial cellulites to ocular and cerebral extension. The diagnosis of mucormycosis was not initially evoked, but confirmed tardively by anatomopathologic and mycologic examinations. The evolution was favourable in 2 cases by administration of amphotericine B associated with extensive surgical debridement and correction of the diabetes. Two patients had a fatal outcome. This infection has a severe prognosis and necessitates early diagnosis.
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