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  • Title: [Problems in the genetics of peptic ulcer. II. An analysis of the associations of the disease with certain simply heritable traits].
    Author: Sharets IuD, Al'tshuler BA, Lebedeva RP, Melikova MIu.
    Journal: Genetika; 1979 Dec; 15(12):2225-32. PubMed ID: 116905.
    Abstract:
    The research of distribution of blood group ABO, Rhesus, Lewis, Secretor, C5+-component of choline esterase and the ability to taste PTC among Moscow population patients suffering from duodenal ulcer is carried out in comparison with the control. Statistically authentic association of the disease with 0(I) blood group, unsecretor and the association of joint signs (coefficients of association are 1.32, 2.17 and 2.62 respectively) is found. Authenticity of relation with disease is not proved during the investigation of other signs. The values of risk to fall ill for the patients possessing and not possessing the signs of duodenal ulcer are obtained (concerning separate factors and joint factors). It is established that the combination of 0(I) blood group and unsecretor increases the risk of the diseases in 2.4 times as compared with the patients possessing A, B, AB blood groups and secretors.
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