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  • Title: Estrogen secretion and its relation to corpus luteum formation in monkeys (Macaca fascicularis) given melatonin.
    Author: Fiske VM, MacDonald GJ.
    Journal: Fertil Steril; 1975 Jun; 26(6):609-12. PubMed ID: 1169173.
    Abstract:
    Daily injection of 10 mg of melatonin from the 7th through the 17th day of the menstrual cycle in the crab-eating monkey delays the appearance of increased secretion of progesterone or prevents it altogether. In the cycles following melatonin treatment, the time in the cycle when the preovulatory estrogen rise occurs is more variable and the frequency of a second estrogen peak increases.
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