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  • Title: A signal/noise analysis of quasi-static MR elastography.
    Author: Bishop J, Samani A, Sciarretta J, Luginbuhl C, Plewes DB.
    Journal: IEEE Trans Med Imaging; 2001 Nov; 20(11):1183-7. PubMed ID: 11700744.
    Abstract:
    In quasi-static magnetic resonance elastography, strain images of a tissue or material undergoing deformation are produced. In this paper, the signal/noise (S/N) ratio [SNR] of elastographic strain images, as measured by a phase-contrast technique, is analyzed. Experiments are conducted to illustrate how diffusion-mediated signal attenuation limits maximum strain SNR in small displacement cases, while the imaging point-spread function limits large displacement cases. A simple theoretical treatment agrees well with experiments and shows how an optimal displacement encoding moment can be predicted for a given experimental set of parameters to achieve a maximum strain SNR. A further experiment demonstrates how the limitation on strain SNR posed by the imaging point-spread function may potentially be overcome.
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