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  • Title: Seborrheic keratosis with compound nevus, junctional nevus and basal cell carcinoma in the same lesion.
    Author: Betti R, Menni S, Cerri A, Vergani R, Crosti C.
    Journal: Dermatology; 2001; 203(3):265-7. PubMed ID: 11701986.
    Abstract:
    Seborrheic keratosis can be associated with different neoplasms such as basal cell carcinomas, squamous cell carcinomas and melanomas. We describe an unusual case of a man who presented with a brown plaque on his back. The clinical diagnosis was melanoma. Histopathologic examination of the lesion revealed four neoplasms: a compound nevus, a junctional nevus, a superficial basal cell carcinoma and a seborrheic keratosis. Although this association most likely represents a chance phenomenon, we discuss the possibility that the seborrheic keratosis developed from the nevus, and that subsequently the junctional nevus and the basal cell carcinoma developed from the seborrheic keratosis.
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