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  • Title: Inhaled nitric oxide for primary pulmonary hypertension in pregnancy.
    Author: Lam GK, Stafford RE, Thorp J, Moise KJ, Cairns BA.
    Journal: Obstet Gynecol; 2001 Nov; 98(5 Pt 2):895-8. PubMed ID: 11704193.
    Abstract:
    BACKGROUND: Primary pulmonary hypertension is a rare and dangerous entity in pregnancy. Previous studies have found a 35-50% maternal mortality rate in the peripartum period. To date, most reports have described treatment of these patients with diuretics, digoxin, and calcium-channel blockers. CASE: We describe the successful treatment of a primigravida with severe primary pulmonary hypertension. We used elective intubation before labor, inhaled nitric oxide therapy, and assisted vaginal delivery with epidural anesthesia that resulted in a viable infant and survival of the mother. CONCLUSION: Nitric oxide can be used to successfully treat primary pulmonary hypertension in pregnancy.
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