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  • Title: Preclinical phase of polycythemia vera in pregnancy.
    Author: Subtil D, Deruelle P, Trillot N, Jude B.
    Journal: Obstet Gynecol; 2001 Nov; 98(5 Pt 2):945-7. PubMed ID: 11704215.
    Abstract:
    BACKGROUND: In some cases, complications of pregnancy are related to thrombophilia. We describe a preclinical phase of polycythemia vera. CASE: A woman, who experienced perinatal deaths in her first two pregnancies, was diagnosed with polycythemia vera during antenatal counseling for a third pregnancy. During this pregnancy, phlebotomies, low molecular weight heparin, and low-dose aspirin treatments resulted in the delivery of a healthy baby. CONCLUSION: Polycythemia vera is a rare condition in women of childbearing age and can exist in a preclinical phase for many years. During pregnancy, it can cause severe but preventable thrombotic complications of placental origin.
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