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  • Title: [Two cases of multiple liver metastases of colon cancer with systemic irinotecan and hepatic arterial injection of 5-FU].
    Author: Nakamura Y, Kamigaki T, Tamura T, Kunimoto Y, Habara K, Fukumoto S, Iwasaki T, Nakamura T, Ku Y, Kuroda Y.
    Journal: Gan To Kagaku Ryoho; 2001 Oct; 28(11):1772-5. PubMed ID: 11708031.
    Abstract:
    We describe two patients with multiple liver metastases of colon cancer, who simultaneously received systemic irinotecan and hepatic arterial injection of 5-FU. In both cases, a notable partial response (more than 80%) in the hepatic metastases was observed. The patients could undergo chemotherapy without remarkable side-effects as out-patients. In the future, we shall perform a clinical study to evaluate the safety and dose limiting toxicity for the present combined chemotherapy.
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