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  • Title: Detection of mammaglobin mRNA in the plasma of breast cancer patients.
    Author: Gal S, Fidler C, Lo YM, Chin K, Moore J, Harris AL, Wainscoat JS.
    Journal: Ann N Y Acad Sci; 2001 Sep; 945():192-4. PubMed ID: 11708478.
    Abstract:
    It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT-PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. We aimed to detect cell-free mammaglobin mRNA in the plasma of breast cancer patients and to investigate whether it can be used as a marker for diagnosis of breast cancer.
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