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  • Title: Choroidal hemangioma treated with photodynamic therapy using verteporfin.
    Author: Madreperla SA.
    Journal: Arch Ophthalmol; 2001 Nov; 119(11):1606-10. PubMed ID: 11709010.
    Abstract:
    OBJECTIVE: To describe a new treatment for vision loss caused by subretinal fluid associated with circumscribed choroidal hemangioma. METHODS: Three patients were treated with photodynamic therapy using verteporfin for injection (Visudyne; QLT Phototherapeutics Inc, Vancouver, British Columbia). All patients had pretreatment and posttreatment fluorescein angiography and ultrasonography. Treatment parameters used were verteporfin, 6 mg/m(2), and laser light at 689 nm delivered at 50 J/cm(2) with an intensity of 600 mW/cm(2) for 83 seconds. RESULTS: All patients had complete resolution of subretinal fluid within 2 weeks of treatment. Fluorescein angiography performed 2 to 4 weeks after treatment showed absence of tumor leakage. All eyes had reduced tumor thickness or complete flattening. Visual acuity was improved in each eye. Average follow-up was 5.3 months. No complications were noted. CONCLUSION: Photodynamic therapy with verteporfin is effective in eliminating subretinal fluid and improving vision in patients with circumscribed choroidal hemangioma.
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