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  • Title: Effect of sodium hypochlorite and EDTA on mercury released from amalgam.
    Author: Rotstein I, Karawani M, Sahar-Helft S, Mor C, Steinberg D.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2001 Nov; 92(5):556-60. PubMed ID: 11709693.
    Abstract:
    OBJECTIVES: The effect of sodium hypochlorite (NaOCl) and EDTA on mercury released from dental amalgam was assessed in vitro. STUDY DESIGN: Fifty-six samples of dental amalgam of similar size were prepared and exposed to a 10-mL solution of either 1% NaOCl, 3% NaOCl, 10% EDTA in 1% NaOCl, or 10% EDTA in 3% NaOCl for periods of 20, 40, and 60 minutes. Mercury concentrations in the solutions were measured by using a cold-vapor atomic absorption Mercury Analyzer System, and the differences between the groups were statistically analyzed. RESULTS: All amalgam samples exposed to 1% NaOCl and 3% NaOCl-either alone or in combination with EDTA-released mercury into the solutions. Mercury release was significantly higher in the test groups than in the EDTA, distilled water, or phosphate buffer controls (P <.001). Increase in the mean concentration levels of mercury in solution was time-dependent and directly related to NaOCl concentration. The addition of EDTA caused a reduction in mercury levels detected in solution, which was more significant in amalgam samples exposed to 1% NaOCl combined with EDTA (P <.001). CONCLUSIONS: NaOCl solutions commonly used for root canal cleaning and shaping cause mercury release from dental amalgam and may alter its chemo-physical properties as a sealant for root perforations.
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