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  • Title: Initial orthostatic hypotension as a cause of recurrent syncope: a case report.
    Author: Wieling W, Harms MP, Kortz RA, Linzer M.
    Journal: Clin Auton Res; 2001 Aug; 11(4):269-70. PubMed ID: 11710801.
    Abstract:
    A 60-year-old male patient with recurrent unexplained syncope on standing was studied. During continuous, noninvasive blood pressure (BP) recording with a Finapres device, an abnormally large and symptomatic initial decrease in systemic BP was documented. After 2 minutes of standing, BP had recovered. The transient decrease in BP was attributed to the use of a combination of antidepressants known to interfere with sympathetic function. This case shows the importance of continuous, noninvasive BP measurement on standing: routine intermittent BP recording would have missed the abnormality. In patients using medications such as antidepressants, initial transient hypotension should be considered as the cause of falls and syncope.
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