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  • Title: Regression of multifocal, skin-restricted, CD30-positive large T-cell lymphoma with interferon alfa and bexarotene therapy.
    Author: French LE, Shapiro M, Junkins-Hopkins JM, Vittorio CC, Rook AH.
    Journal: J Am Acad Dermatol; 2001 Dec; 45(6):914-8. PubMed ID: 11712039.
    Abstract:
    We report the case of a 43-year-old male patient with persistent multifocal, skin-restricted, CD30-positive, large T-cell lymphoma. Combination therapy of systemic interferon alfa and oral bexarotene was initiated on an experimental basis in the hope of circumventing therapies such as methotrexate, radiotherapy, or multiple-agent chemotherapy that may be required in such cases. This treatment was associated with rapid and marked regression of the patient's cutaneous lesions.
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