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  • Title: Systemic allergic contact dermatitis to 8-methoxypsoralen (8-MOP).
    Author: Ravenscroft J, Goulden V, Wilkinson M.
    Journal: J Am Acad Dermatol; 2001 Dec; 45(6 Suppl):S218-9. PubMed ID: 11712064.
    Abstract:
    Photochemotherapy with psoralens and UVA (PUVA) is widely used in the treatment of psoriasis and many other skin conditions. Cutaneous adverse reactions to 8-methoxypsoralen (8-MOP) appear to be rare and may be difficult to distinguish from phototoxicity or UV-induced polymorphic light eruption. We describe a patient who had a systemic allergic contact dermatitis to 8-MOP develop during her second course of PUVA treatment for psoriasis.
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