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Title: Role of alendronate and risedronate in preventing and treating osteoporosis. Author: Peters ML, Leonard M, Licata AA. Journal: Cleve Clin J Med; 2001 Nov; 68(11):945-51. PubMed ID: 11718433. Abstract: Alendronate and risedronate, the two oral bisphosphonates approved in the United States for preventing and treating osteoporosis, have never been compared in direct head-to-head trials, but they appear to have similar pharmacokinetics, drug interactions, adverse effect profiles, and efficacy. Alendronate, however, can be given as a once-weekly dose, whereas risedronate is not yet available in this dosage form. On the other hand, alendronate is not approved for preventing glucocorticoid-induced osteoporosis, whereas risedronate carries this indication.[Abstract] [Full Text] [Related] [New Search]