These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Biological activity in human neutrophils of di-tripeptides, analogues of the chemotactic fMLP.
    Author: Cavicchioni G, Turchetti M, Spisani S.
    Journal: Bioorg Med Chem Lett; 2001 Dec 17; 11(24):3157-9. PubMed ID: 11720864.
    Abstract:
    for-Met-Ser(for-Met-Leu-Phe)-Phe-OMe 1 and for-Met-Lys(for-Met-Leu-Phe)-Phe-OMe 2 were synthesized in order to investigate biological activities on human neutrophils of crosslinked di-tripeptides. Our results seem to highlight that the tested di-tripeptides (i) do not step up chemotaxis, (ii) can elicit superoxide anion production which is dependent on the nature of the residue at position 2, chosen in the tripeptide that is crosslinked to the fMLP-OMe.
    [Abstract] [Full Text] [Related] [New Search]