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  • Title: Is there any significance for intracellular crystals in plasma cells from patients with monoclonal gammopathies?
    Author: Gardais J, Geneviève F, Foussard C, Delisle V, Zandecki M.
    Journal: Eur J Haematol; 2001 Aug; 67(2):119-22. PubMed ID: 11722600.
    Abstract:
    Several plasma cells morphological changes have been described in monoclonal gammopathies, including intracytoplasmic crystals. We report one case of indolent kappa-chain multiple myeloma with renal insufficiency, featuring plasma cells with Auer-rod-like intracytoplasmic inclusions. The relationship between such aberrations and those found in multiple-myeloma-associated adult Fanconi syndrome is discussed. The significance of intracellular storage and crystallisation of immunoglobulin within plasma cells remains partially unknown.
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