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  • Title: Prevention of heterotopic ossification after total hip replacement: a prospective comparison of indomethacin and salmon calcitonin in 60 patients.
    Author: Günal I, Hazer B, Seber S, Göktürk E, Turgut A, Köse N.
    Journal: Acta Orthop Scand; 2001 Oct; 72(5):467-9. PubMed ID: 11728072.
    Abstract:
    We did a prospective consecutive study of prophylaxis for heterotopic ossification (HO) comparing indomethacin (100 mg/day) and salmon calcitonin (3 MRC-U/kg/day) for 14 days. Each group consisted of 30 patients. 19 patients in the indomethacin group and 2 in the calcitonin group developed HO. We conclude that use of calcitonin in the prophylaxis of HO after total hip replacement is more effective than indomethacin.
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