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  • Title: FBG and TC/HDL ratios in type 2 diabetes mellitus.
    Author: Hanif R, Sattar A, Qayum I.
    Journal: J Ayub Med Coll Abbottabad; 2001; 13(2):42-4. PubMed ID: 11732222.
    Abstract:
    BACKGROUND: Presence of dyslipidemia, i.e. raised Total Cholesterol (TC) and decreased High Density Lipoproteins (HDL) is an established phenomenon in type 2 diabetes mellitus. Its relationship to the fasting blood sugar (FBG) level in both diabetics and non-diabetics has yet to be established. The present study aims to show such a relationship. METHODS: 150 subjects were selected and divided into two groups, one of 50 controls (non-diabetics), the other of 100 patients with type 2 diabetes mellitus. Their FBG levels were determined by enzyme oxidase method, and their TC and HDL levels were determined using a standard kit method. RESULTS: FBG and TC:HDL ratios were increased in the patient group (p = < 0.001). Comparison of FBG and TC:HDL ratios revealed a highly significant rise (p = < 0.001) in the patient group. FBG with TC:HDL ratios between both groups showed a positive correlation (r = 0.554). CONCLUSION: The results of the present study suggest an association between FBG and TC:HDL ratios, which may be a contributory factor to the increased prevalence of coronary artery disease in patients with type 2 diabetes mellitus.
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