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  • Title: Synthesis of 3,4-disubstituted isoquinolines via palladium-catalyzed cross-coupling of o-(1-alkynyl)benzaldimines and organic halides.
    Author: Dai G, Larock RC.
    Journal: Org Lett; 2001 Dec 13; 3(25):4035-8. PubMed ID: 11735578.
    Abstract:
    [reaction: see text] 3,4-Disubstituted isoquinolines have been prepared in good yields by the palladium-catalyzed cross-coupling of N-tert-butyl-o-(1-alkynyl)benzaldimines with aryl, allylic, and alkynyl halides.
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