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  • Title: Unusual etiology of visual loss in an HIV-infected patient due to endogenous endophthalmitis.
    Author: Miailhes P, Labetoulle M, Naas T, Guibert M, Bourée P, Frau E, Nordmann P, Galanaud P.
    Journal: Clin Microbiol Infect; 2001 Nov; 7(11):641-5. PubMed ID: 11737091.
    Abstract:
    Disseminated candidiasis, especially ocular infections such as endophthalmitis, is uncommon in HIV-infected patients. We report a case of candidal endophthalmitis in an HIV-positive non-drug-user patient, following candidemia from a cutaneous abscess at the site of a peripheral catheter. Ocular disease was revealed by a visual decrease in the left eye. DNA analysis using RAPD showed identical patterns of Candida albicans isolated from the skin and eye. Combination therapy with high-dose fluconazole and intravenous amphotericin B was performed. Two intravitreal amphotericin B injections and a vitrectomy were administered because of an amblyopic right eye and severe vitritis. The outcome was favorable without relapse at 18 months.
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