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  • Title: [Spectrophotometric determination of methaqualone in biologic material].
    Author: Kerde C.
    Journal: Arzneimittelforschung; 1975 Mar; 25(3):363-5. PubMed ID: 1174032.
    Abstract:
    A rapid and simple spectrophotometric procedure for the determination of 2-methyl-3-o-tolyl-4(3H)-quinazolinone (methaqualone) in biological material is described. After extraction of the specimen with chloroform and washing with 0.5 N sodium hydroxide and 0.5 N sulfuric acid methaqualone is extracted with 5 ml 50% sulfuric acid and read in a spectrophotometer at 234 nm. The procedure is suitable to determine serum levels of methaqualone after a therapeutic dose.
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