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  • Title: Interface-mediated synthesis of hydroxyapatite.
    Author: Pham MT, Matz W, Reuther H, Richter E, Steiner G, Oswald S.
    Journal: J Biomed Mater Res; 2002 Feb; 59(2):254-8. PubMed ID: 11745560.
    Abstract:
    Interfacing of water vapor and titanium was employed for a controlled synthesis of surface-supported hydroxyapatite. In this approach, a Ti surface was doped with Ca and P by ion implantation and then subjected to a hydrothermal treatment in a water vapor autoclave. Ion implantation served to prepare a reactive blend of finely dispersed reactants in a stoichiometric ratio incorporated within the network of an outermost layer of the substrate surface. Needle-like carbonate hydroxyapatite in an overlay was identified to deposit onto the surface. The results suggest interface-mediated thin film formation and phase transformation.
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