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  • Title: In vitro synergy of caspofungin and amphotericin B against Aspergillus and Fusarium spp.
    Author: Arikan S, Lozano-Chiu M, Paetznick V, Rex JH.
    Journal: Antimicrob Agents Chemother; 2002 Jan; 46(1):245-7. PubMed ID: 11751145.
    Abstract:
    We investigated the in vitro interaction of caspofungin and amphotericin B for clinical isolates of Aspergillus and FUSARIUM: Synergy tests were performed using the checkerboard method and following the NCCLS M38-P guidelines in Antibiotic Medium 3 broth supplemented to 2% glucose. Antagonism was not observed for any of the isolates tested. Caspofungin and amphotericin B were synergistic or synergistic to additive for at least half of the isolates.
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