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  • Title: Effects of dopamine on isolated canine coronary arteries.
    Author: Toda N, Goldberg LI.
    Journal: Cardiovasc Res; 1975 May; 9(3):384-89. PubMed ID: 1175184.
    Abstract:
    Dopamine contracted isolated canine coronary arteries at initial concentrations of 5 times 10(-6) mol/l. In the presence of phentolamine or phenoxybenzamine and after contraction of the arteries with K+ or prostaglandin F2alpha, dopamine caused dose-related relaxation at initial concentrations of 5 times 10(-6) mol/l and 10(-6) mol/l. Propranolol, 10(-6) mol/l, and haloperidol, 10(-5) mol/l, did not antagonize the relaxation.
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