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  • Title: New cytotoxic butanolides from Litsea acutivena.
    Author: Cheng HI, Lin WY, Duh CY, Lee KH, Tsai IL, Chen IS.
    Journal: J Nat Prod; 2001 Dec; 64(12):1502-5. PubMed ID: 11754599.
    Abstract:
    Six new compounds, including one nor-neolignan, dehydroxymethylailanthoidol (1), and five butanolides, litseakolide D (2), litseakolide E (3), litseakolide F (4), litseakolide G (5), and isolincomolide D (6), were isolated from the leaves of Litsea acutivena. Their structures were elucidated from spectral analyses. The butanolides (2-6) showed significant cytotoxic activity against P-388, A549, and HT-29 cell lines in vitro.
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