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  • Title: Cytotoxic polyacetylenic alcohols from the marine sponge Petrosia species.
    Author: Lim YJ, Lee CO, Hong J, Kim DK, Im KS, Jung JH.
    Journal: J Nat Prod; 2001 Dec; 64(12):1565-7. PubMed ID: 11754614.
    Abstract:
    New polyacetylenic alcohols (1-5) have been isolated as cytotoxic principles from the marine sponge Petrosia sp. The compounds were particularly cytotoxic against a human melanoma cell line (SK-MEL-2). The gross structures were established on the basis of NMR and MS data, and the absolute configuration was determined by the modified Mosher's method.
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