These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Four new bioactive pyrrole-derived alkaloids from the marine sponge Axinella brevistyla.
    Author: Tsukamoto S, Tane K, Ohta T, Matsunaga S, Fusetani N, van Soest RW.
    Journal: J Nat Prod; 2001 Dec; 64(12):1576-8. PubMed ID: 11754618.
    Abstract:
    Four new alkaloids (1-4) were isolated from the marine sponge Axinella brevistyla, and their structures were determined on the basis of spectroscopic analysis. The alkaloids 1-4 were antifungal against the yeast Saccharomyces cerevisiae at <1.0, <1.0, 30, and 100 microg/disk, respectively. Compounds 1-3 also exhibited cytotoxicity against L1210 cells with IC(50) values of 1.1, 0.66, and 2.5 microg/mL, respectively.
    [Abstract] [Full Text] [Related] [New Search]