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  • Title: Effect of X-irradiation on vitamin B12 binding capacity to intrinsic factor.
    Author: D'Souza DW, Vakil UK, Sreenivasan A.
    Journal: Environ Physiol Biochem; 1975; 5(4):217-25. PubMed ID: 1175581.
    Abstract:
    The effects of whole-body X-irradiation on vitamin B12-protein complex formation in gastric juice after oral administration of [57Co]-B12 have been studied. Two proteins with B12-binding activity have been isolated by gel filtration from gastric juice. 57Co-activity, recovered from B12-protein complex in gastric juice, is found to be about 30% less in the X-irradiated rat. In serum, vitamin B12 is mainly associated with alpha1-globulin. Radioactivity distribution in serum globulins after intraperitoneal injection of [57Co]-B12 was similar in control and X-irradiated rats.
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