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  • Title: [Clinicopathological features of malignant ovarian neoplasms arising from ovarian endometriosis: a report of 26 cases].
    Author: Qu Y, Wang L, Zhu H.
    Journal: Zhonghua Fu Chan Ke Za Zhi; 2001 Aug; 36(8):470-2. PubMed ID: 11758181.
    Abstract:
    OBJECTIVE: To clarify the features of malignant ovarian neoplasms arising from ovarian endometriosis. METHODS: A total of 26 women with malignant ovarian neoplasms arising from ovarian endometriosis were analyzed retrospectively. RESULTS: Dysmenorrhea and pelvic mass were the most common clinical features. Among 18 cases who underwent B-ultrasound or color doppler ultrasound examination, solid foci in the pelvic masses were found in 10 cases. The main histologic types of ovarian malignancy were endometrioid adenocarcinoma and clear cell carcinoma. Microscopically atypical endometriosis with the tumors were found in 15 cases. International Federation of Gynecology and Obstetrics stage: stage I 21(81%) cases, stage II 3(12%) cases, stage III 2 (8%) cases. CONCLUSIONS: Clinical diagnosis of malignant ovarian neoplasms arising from ovarian endometriosis in early stage is difficult, and B-ultrasound examination is more valuable for diagnosis. It is suggested that close serutiny of endometrial hyperplasia, cellular atypia and malignancy in ovarian endometriosis be essential to understand the origin and development of malignant neoplasms arising from ovarian endometriosis.
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