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  • Title: Brain PET and technetium-99m-ECD SPECT imaging in Lhermitte-Duclos disease.
    Author: Ogasawara K, Yasuda S, Beppu T, Kobayashi M, Doi M, Kuroda K, Ogawa A.
    Journal: Neuroradiology; 2001 Nov; 43(11):993-6. PubMed ID: 11760808.
    Abstract:
    Two patients with Lhermitte-Duclos disease were evaluated by brain positron emission tomography (PET) and technetium-99m-ethyl cysteinate dimer (99mTc-ECD) single-photon emission computed tomography (SPECT). In the lesions in both patients, hyperperfusion was detected on cerebral blood flow images obtained by PET, and hyperactivity by standard 99mTc-ECD SPECT. Dynamic 99mTc-ECD SPECT images demonstrated a plateau of activity in each lesion. These findings suggest that lesions in Lhermitte-Duclos disease have a retention mechanism for 99mTc-ECD equivalent to that of normal neural tissue.
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