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  • Title: [The role of hyperlactatedehydrogenasemia in induction of metabolic disorders in the body].
    Author: Gil'miiarova FN, Radomskaia VM, Baisheva GM, Kretova IG, Kleĭman MS, Pervova IuV.
    Journal: Vopr Med Khim; 2001; 47(5):469-76. PubMed ID: 11766256.
    Abstract:
    The effect of intravenous administration of lactate dehydrogenase (5000 E/kg) on some metabolic parameters was investigated. The hyperenzymemia was accompanied by changes of metabolite content (glutamate, 2-oxoglutarate, lactate, dihydroxyacetone phosphate) and enzyme activities (aldolase, lactate dehydrogenase, transaminase) in heart, liver and skeletal muscles. Intravenously administered tritiated lactate dehydrogenase was preferentially found in skeletal muscles, liver, kidneys and some other organs.
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