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  • Title: [Contribution to etiology of otitis media with effusion].
    Author: Wierzbicka M, Szyfter W, Ławniczak M, Kamiński B.
    Journal: Otolaryngol Pol; 2001; 55(4):405-7. PubMed ID: 11766318.
    Abstract:
    BACKGROUND: Otitis media with effusion is characterized by gathering and retaining of effusion within the tympanic cavity and the structures of the mastoid bone. The aim of this study was to explain the role of immunological reaction in pathogenesis and development of this disease. MATERIAL AND METHOD: The studied group comprised 6 patients aged between 7 and 14 years. The effusion present within the tympanic cavity was aspired and then the agarare gel immunoelectrophoresis was performed. After 24 hours the precipitation stripes of the IgA and IgG were analysed. Blood serum specimens were also collected in the studied group. After centifrugation, blood serum concentrations of IgA and IgG were evaluated. RESULTS: IgA and IgG were present in the effusion taken from the tympanic cavity in all examined cases. The level of IgA was higher in older individuals.
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