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  • Title: [Spontaneous bacterial peritonitis in hepatic cirrhosis with ascites: incidence, bacteriology and mortality in Uruguay].
    Author: Rubinstein P, Morales M, Pandiani A, Bagattini JC.
    Journal: Acta Gastroenterol Latinoam; 2001 Oct; 31(4):307-12. PubMed ID: 11766541.
    Abstract:
    Spontaneous bacterial peritonitis (SBP) is a frequent and severe complication of cirrhotic patients with ascites. In order to analyze the incidence, bacteriology and in-hospital mortality, we studied 64 consecutive patients with cirrhosis and ascites (47 males, 17 females average age 59 years) hospitalized in a general adults 3rd level hospital (Pasteur hospital, Montevideo, Uruguay), between September 1998 and May 2000. The diagnostic criteria was more than 250 polymorphonuclear cells/cu.mm. in ascitic fluid and/or a positive culture. We found 17 SBP in 17 patients (10 males 24-81 years) which means an incidence of 26.56%. 15 alcoholic cirrhosis and 2 autoimmune disease. 12% (2/17) were asymptomatic; 8/17 were SBP culture positive (5 E. Coli, 2 St. Pneumoniae, 1 Klebsiella sp.), and 9 were culture negative. The mortality rate associated with SBP was 47% (8/17), greater than the cirrhotic group without SBP (12.7% p < 0.01).
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