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  • Title: Pathological fracture complicating epidural local anaesthetic opioid infusion for cancer pain.
    Author: Amanor-Boadu SD, Jack TM.
    Journal: West Afr J Med; 2001; 20(2):179-80. PubMed ID: 11768023.
    Abstract:
    Two cases of severe bone pains from metastatic cancer, without clinical or radiological evidence of fractures on admission, are presented. Pain control and mobilization were achieved initially with local anaesthetic-opioid epidural infusion. Subsequent loss of analgesia prompted a re-examination, which revealed pathological fractures of the femur. Internal fixation of the fractures resulted in good control such that strong opioids were no longer required.
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