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  • Title: [Effects of Streptococcus sanguis on blood composition, blood pressure and cardiac dysfunction in rabbis].
    Author: Chen H, Zhao M, Li J.
    Journal: Zhonghua Kou Qiang Yi Xue Za Zhi; 2001 Sep; 36(5):354-6. PubMed ID: 11769649.
    Abstract:
    OBJECTIVE: To investigate effect of streptococcus sanguis on blood cell and cardiopulmonary changes. METHODS: 133-79 strains of streptococcus sanguis (aggregation positive) were infused intravenously into rabbits. Before and 5, 10, 20, 30, 45, 60 min after infuse platelets count, leukocytes count, blood pressure and ECG were measured. RESULTS: After infused intravenously, both platelets and leukocytes count decreased remarkably (P < 0.01, n = 12). The ECG showed ST segment depression (> 0.06 mV). Diphasic blood pressure occurred (first hypertensive then hypotensive). CONCLUSIONS: Streptococcus sanguis 133-79 strains in circulation system might cause myocardia ischemia, blood pressure changes, peripheral circulation platelets and leukocytes decrease remarkably.
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