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  • Title: [Pure primitive dysautonomia or Bradbury-Eggleston syndrome. Report of 3 cases].
    Author: Marouene H, Bellassoued M, Mnif M, Rekik N, Chouayakh F, Zouari N, Abid M.
    Journal: Tunis Med; 2001; 79(6-7):383-8. PubMed ID: 11771436.
    Abstract:
    The primary autonomic failure (Bradbury-Eggleston syndrome) is rare. We report three cases (two females and one male) who are 55 year old with orthostatic hypotension, tachycardia, and other signs of dysautonomia. They hadn't a pyramidal, extrapyramidal or cerebellar syndromes. The other causes of postural hypotension are excluded. The autonomic dysfunction was confirmed by autonomic reflex tests and by evaluating of cardiac reflex function; these included heart rate responses to deep breathing and to the valsalva maneuver. Hypotension occurs in a variety of clinical setting; ascertainment of the cause is by non means easy. Primary autonomic failure remains a diagnostic category based on exclusion; its pathophysiology isn't well know and its treatment is only symptomatic.
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